Name Corticotropin-Releasing Hormone Receptor 2 (CRHR2) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human CRHR2. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human CRHR2 cell-based assay; cell-based high-throughput screening of human CRHR2 agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |