Name Muscarinic Acetylcholine Receptor M4 (CHRM4) ACTOne™ Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human CHRM4. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human CHRM4 cell-based assay; cell-based high-throughput screening of human CHRM4 agonist/antagonist. Size 1x 106 cells Detection FlexStation or Microplate reader |