产品介绍
| Name Cannabinoid Receptor 1 (CB1) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human CB1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FDSS, FLIPR, or a fluorescence microplate reader. Application cAMP dependent human CB1 receptor cell-based assay; Cell-based high-throughput screening of human CB1 receptor agonists/antagonists. Size 2x 106 cells Detection FlexStation or microplate reader |