Name Amylin 3 Receptor (AMY3) ACTOneTM Stable Cell Line Description This cell line expresses a recombinant human RAMP3. The parental cell line is Calcitonin Receptor (CALCR) ACTOne Stable Cell Line (CL-01-CALCR) that is HEK-293-CNG cell line that expresses a recombinant human CALCR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP assay for Gs-coupled human Amylin 3 receptor Size 1x 106 cells (before freezing) Detection FlexStation or Microplate reader |