Name Adenosine A2B Receptor (ADORA2B) ACTOne™ Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human ADORA2B. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human ADORA2B cell-based assay; cell-based high-throughput screening of human ADORA2B agonists/antagonists Size 1x 106 cells Detection FlexStation or Microplate reader |