Remdesivir is a broad-spectrum antiviral developed by Gilead Sciences. Remdesivir is a prodrug, and upon entry into cells, it is metabolized into the nuceotide triphosphate GS-441524.
Remdesivir was investigated for activity for Ebola virus, but it was found to have activity against the coronavirus (CoV) family of viruses including severe acute repiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome (MERS-CoV), and in vitro activity against SARS-CoV2.