Pretomanid P142-100MG

产品介绍

Pretomanid is a bicyclic nitroimidazole and small molecule pro-drug that is active against actively replicating and hypoxic non-replicating Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). It is activated by deazaflavin-dependent nitroreductase. Other mono- and multidrug-resistant strains of M. tuberculosis exhibited comparable susceptibilities to Pretomanid, indicating no cross-resistance with current anti-TB drugs.