SCV2-PsV-SA ; SARS-CoV-2 Pseudoviral Particles (South Africa Variant, beta, B.1.351)

产品介绍

Name SARS-CoV-2 Pseudoviral Particles, Beta Variant (South Africa B.1.351) Description The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein of the Beta Variant (South Africa B.1.351, a.k.a. 20H/501Y.V2, formerly 20C/501Y.V2) (GISAID sequence accession number: EPI_ISL_736980). MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV. Applications Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. Size 5 ml, for one multi-well plate. Pseudoviral particles per mL ~ 1.0E+08 Storage  -70oC. Shipped on dry ice. Note 1. Amenable to HTS format (96-well, 384-well and 1536-well format). 2. HEK293-hACE2 stable cell lines are available seperately (Cat.# CL-hACE2-001, CL-hACE2-002)