Pimecrolimus P083-500MG

产品介绍

Pimecrolimus is a semi-synthetic, macrocyclic lactone derived from ascomycin by activation of the 32-hydroxy group with a triflate ester, and nucleophilic substitution with chloride under phase transfer conditions to provide the chloro analogue. Pimecrolimus has been targeted for treatment of inflammatory skin disorders. Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties.

Pimecrolimus is soluble in ethanol, methanol, DMF or DMSO, but is practically insoluble in water.