Piperacillin is the monohydrate form of Piperacillin, a semi-synthetic, extended spectrum fungistatic β-lactam fourth-generation ureidopenicillin. It was developed by Toyama Chemical Co, Tokyo, Japan and is derived from Ampicillin. Piperacillin is commonly used in combination with the β -lactamase inhibitor Tazobactam. It can be used to study multidrug resistance.
Piperacillin is sparingly soluble in aqueous solution.