SCV2-PsV-222V ; SARS-CoV-2 (A226V) Pseudoviral Particles

产品介绍

Name SARS-CoV-2 Pseudoviral Particles, D614G-A222V Description The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine Leukemia Virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein of the 20E (EU1) variant carrying (Genbank Accession # QHD43416.1, p.222A-->V, p.614D-->G). MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV. Applications Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. Size 5 ml, for one multi-well plate. Pseudoviral particles per mL ~ 1.0E+07 Storage  -70oC. Shipped on dry ice. Note 1. Amenable to HTS format (96-well, 384-well and 1536-well format). 2. HEK293-hACE2 stable cells are available seperately (Cat.# CL-hACE2-001, CL-hACE2-002)