Name SARS-1 Coronavirus Pseudoviral Particles Description Our SARS-1 Coronavirus Pseudoviral Particles are replication-deficient Maloneymurine Leukemia Virus (MLV or MuLV) pseudotyped with the SARS-CoV/BJ02 (2003) virus spike protein (Genbank Accession # AY278487). MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV. Applications Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV virus entry and viral protein translation with spike protein of SARS-CoV/BJ02; 2) measuring the activity of and screening for neutralizing antibody against SARS coronavirus. Size 5 ml, for one multi-well plate. Pseudoviral particles per mL ~ 1.0E+08 Storage -70 C. Shipped on dry ice. Note 1. Amenable to HTS format (96-well, 384-well and 1536-well format). 2. HEK293-hACE2 stable cell lines are available seperately (Cat..# CL-hACE2-001, CL-hACE2-002) |