Name MERS-CoV Pseudoviral Particles Description Our MERS Pseudoviral Particles are replication-deficient Maloneymurine Leukemia Virus (MLV or MuLV) pseudotyped with the MERS virus spike protein (Genbank Accession # AHY21469.1). MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Applications Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block MERS virus entry and viral protein translation with spike protein of MERS; 2) measuring the activity of and screening for neutralizing antibody against MERS virus. Size 5 ml, for one multi-well plates. Pseudoviral particles per mL ~ 1.0E+08 Storage -70 C. Shipped on dry ice. Note Amenable to HTS format (96-well, 384-well and 1536-well format). |