Netilmicin Sulfate is the sulfate salt form of Netilmicin, a semisynthetic, broad-spectrum aminoglycoside antibiotic. It is a 1-N-ethyl derivative of the natural antibiotic sisomycin produced by fermentation of Micromonospora inyoensis that has a similar mechanism of action to Gentamicin. Netilmicin was patented in 1973 by Schering-Plough. It can be used as an analytical standard for antimicrobial susceptibility testing or in studying aminoglycoside resistance.