Kanamycin B, EvoPure® is a highly purified form of Kanamycin B. Kanamycin B is a minor component of the Kanamycin complex, along with C, with Kanamycin A being the major component.
Kanamycn B is a close structural analog of DAA2 and it has an unmethylated 3'-amino group so it can be tested as a surrogate substrate for 3’-deamination.
Kanamycin is a semi-synthetic, broad-spectrum aminoglycoside antibiotic. Kanamycin was isolated from the soil bacterium Streptomyces kanamyceticus in 1957 by Hamao Umezawa at the institute of Microbial Chemistry (Tokyo). Kanamycin inhibits protein synthesis in bacteria and Mycoplasma. It is used to select for transformants (bacteria, fungi, plant, mammalian) which have been successfully transformed with a plasmid containing a Kanamycin resistance gene.
Kanamycin B, EvoPure® is soluble in DMSO.