Imipenem mixture w/cilastatin I005-5MG

产品介绍

Imipenem Mixture w/ Cilastin (syn: Imipenem/Cilastin) is a 1:1 mixture of Imipenem and Cilastin, a combination originally developed by Merck & Co. in 1985 under the trade name Primaxin.

Imipenem is a broad-spectrum carbapenem that is effective against extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae, a group of pathogenic microbes resistant to many first line β-lactam antibiotics and certain cephalosporins. Cilastatin is a chemical substance which inhibits dehydropeptidase (DHP1), a human enzyme that degrades Imipenem. 

Imipenem Mixture w/ Cilastin is soluble in aqueous solution.